Asterias announces continued motor function improvement in phase 1/2a trial for acute SCI

Six AIS-A quadriplegic volunteers received 10 million  AST-OPC1 cells in Asterias Biotherapeutics SCIstar trial. For the five patients who have completed at least 6 months of follow-up all have seen improvements in their motor function, Read more…

Research to reverse spinal cord injury offers renewed hope to 15,000 Australians

Research aiming to reverse the paralyzing effects of spinal cord injuries (SCI) that devastate the lives of so many Australians and their families will soon begin at the University of Technology Sydney (UTS).

Asterias to begin stem cell dose escalation in the Phase 1/2a trial for SCI

The SCiStar Study is a Phase 1/2a clinical trial evaluating the safety and activity of escalating doses of AST-OPC1 cells in newly injured patients with sensory and motor complete cervical spinal cord injury. The three patients in the first cohort…

Implantable tech that restores movement in paralyzed patients available in 2017

Case Western Reserve University’s Institute for Functional Restoration (IFR) and Synapse Biomedical Inc. have entered a partnership to commercialize fully implantable systems that restore muscle function in paralyzed patients. The technology uses electrical stimulation to activate neural pathways and create…

Phase 1/2a stem cell trial for acute spinal cord injury begins

Asterias Biotherapeutics has initiated patient enrolment for its Phase 1/2a clinical trial of AST-OPC1 stem cells for treating newly injured people with complete cervical spinal cord injury. “The Phase 1 study generated a strong package of data regarding the safety of AST-OPC1,” said…

Miami Project Schwann Trial for Chronic SCI Begins Enrollment for 10 people

This new trial will be primarily focused on safety, but in addition it will involve a preliminary evaluation of the efficacy of combining Schwann cells with exercise and rehabilitation. They only have FDA approval to transplant a maximum of 10 people…