Enhancing neuronal activity promotes axon regeneration in adult CNS

Scientists from the Hong Kong University of Science and Technology (HKUST) have demonstrated that axon regenerative capacity can be boosted with the right stimulants on neuronal activity through either an optogenetic or a chemogenetic approach. Read more… | Published paper

Protein combination improves bone regeneration

A UCLA research team has found a combination of proteins that could significantly improve clinical bone restoration. The findings may be a big step toward developing effective therapeutic treatments for bone skeletal defects, bone loss and osteoporosis. Read more… | Published…

Reducing immune response damage in SCI with therapeutic stem cells

Researchers from Case Western Reserve University found that the immune system of spinal cord injury patients can be controlled using a family of therapeutic stem cells known as multipotent adult progenitor cells (MAPC), The MAPCs have the ability to mediate…

Interleukin-37 promotes locomotor recovery in acute spinal cord injuries

An international collaboration of researchers has shown for the first time that Interleukin-37 suppresses the inflammatory response after a spinal cord injury and minimises spinal tissue degeneration and functional disabilities. Although IL-37 was identified 15 years ago, studying its function has proven difficult…

New method to promote regeneration of injured spinal cord nerve cells

A group of small molecule natural products possesses potent neurotrophic properties without some of the shortcomings of protein-based agents. Now, Dartmouth College (New Hampshire USA) researchers have discovered that one of their recently discovered chemical reactions is capable of producing some of…

Chronic pain and depression common in those with spinal cord injury

In a study published in Nature researchers investigate the epidemiology of pain types in patients with spinal cord injury (SCI) according to the International Spinal Cord Injury Pain (ISCIP) classification. Read more…

Nordic Life Science completes first trial of its Spinalon™ pill for chronic paralysis

Developed by Canadian researchers from Laval University and CHU de Québec, Spinalon is an oral pill composed of three active molecules capable together of triggering short bouts of locomotor-like activity in the legs of spinal cord injured patients who had been…

Rats with chronic parvovirus infection show improved recovery from spinal cord injury

A vendor informed researchers in Stockholm, Sweden that they had been shipped rats infected with rat parvovirus type 1a (RPV-1a). They compared these rats with uninfected ones and found that, after spinal cord injury, the RPV-1a-infected rats had significantly better hind limb…