An international collaboration of researchers has shown for the first time that Interleukin-37 suppresses the inflammatory response after a spinal cord injury and minimises spinal tissue degeneration and functional disabilities. Although IL-37 was identified 15 years ago, studying its function has proven difficult as it is not synthesised in mice.
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Beneficial effects of IL-37 after spinal cord injury in mice, PNAS. DOI: 10.1073/pnas.1523212113