{"id":12000,"date":"2022-04-14T12:22:13","date_gmt":"2022-04-14T02:22:13","guid":{"rendered":"https:\/\/www.spinalcure.org.au\/?p=12000"},"modified":"2022-04-28T11:18:52","modified_gmt":"2022-04-28T01:18:52","slug":"new-panel-of-experts-aims-to-mend-the-gap-in-spinal-cord-injuries","status":"publish","type":"post","link":"https:\/\/www.spinalcure.org.au\/research\/new-panel-of-experts-aims-to-mend-the-gap-in-spinal-cord-injuries\/","title":{"rendered":"New panel of experts aims to \u2018mend the gap\u2019 in spinal cord injuries"},"content":{"rendered":"<p><span style=\"color: #000000;\"><b>A new international team of 32 scientists has joined forces to identify areas of promising research in spinal cord injuries. Their first project aims to mend the tiny gaps that form after a traumatic injury, writes <a style=\"color: #000000;\" href=\"https:\/\/www.spinalcure.org.au\/news\/tom-elphicks-story\/\">Tom Elphick<\/a>, SpinalCure Community Ambassador.<\/b><\/span><\/p>\n<p><span style=\"font-weight: 400;\">The team, called Mend The Gap, has recently been established in Canada. It has 32 members from the US, Canada, Europe and Australia including leading experts in fields such as neurology, physics, biomedical engineering, chemistry and ethics.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Their goal is to combine the efforts of these researchers to generate new and impactful discoveries for spinal cord injury research.\u00a0<\/span><\/p>\n<p><iframe loading=\"lazy\" src=\"https:\/\/globalnews.ca\/video\/embed\/8509289\/\" width=\"670\" height=\"372\" frameborder=\"0\" scrolling=\"no\" allowfullscreen=\"allowfullscreen\"><\/iframe><\/p>\n<h2><span style=\"color: #000080;\">Expert team recognises the potential of neurostimulation\u00a0<\/span><\/h2>\n<p><span style=\"font-weight: 400;\">Mend The Gap recognises the potential for neurostimulation to play a big role in spinal cord rehabilitation.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The team has picked out <\/span><a href=\"https:\/\/mendthegap.ubc.ca\/approach\/\"><span style=\"font-weight: 400;\">4 \u2018themes\u2019 that their research will focus on<\/span><\/a><span style=\"font-weight: 400;\">, based on the therapies that show the most promise.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Neurostimulation, or electrical stimulation, is an integral part of their \u2018theme two\u2019 which focuses on helping neurons form connections with one another. After spinal cord damage, neurons need to rebuild connections with one another to be able to send messages from the brain to the limbs. There is some evidence to show that neurostimulation accelerates this process.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">They state that the biological processes of repair are likely to involve a \u201ccombination of drugs, rehabilitation training and electrical stimulation\u201d.\u00a0<\/span><\/p>\n<blockquote><p><span style=\"font-weight: 400;\">\u201cThis is great to see,\u201d commented Duncan Wallace, SpinalCure Executive Director, \u201cas our Scientific Advisory Panel has backed spinal cord neurostimulation because we believe that this could form part of the final cure.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\"><img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-480 alignleft\" src=\"https:\/\/www.spinalcure.org.au\/wp-content\/uploads\/2020\/06\/img-duncanwallace.jpg\" alt=\"Duncan Wallace\" width=\"140\" height=\"139\" \/>\u201cOur eWalk trial and proposed Project Spark both include rehabilitation training and spinal cord stimulation, and it\u2019s good to see this approach\u2014in combination with yet-to-be-identified drugs\u2014 being backed by this international team,\u201d he said.<\/span><\/p><\/blockquote>\n<p><span style=\"font-weight: 400;\">Many r<\/span><a href=\"https:\/\/www.economist.com\/science-and-technology\/spinal-implants-allow-paralysed-people-to-walk-swim-and-cycle-again\/21807596?giftId=501b9a8e-2d60-49fd-b8aa-bc19e103c09e\"><span style=\"font-weight: 400;\">ecent advancements<\/span><\/a><span style=\"font-weight: 400;\"> in neurostimulation technology have proved successful, with researchers in Switzerland using an implanted electrode to help an Italian man walk again after 4 years, for example.<\/span><\/p>\n<h2><span style=\"color: #003366;\">Injectable gels could \u2018mend the gap\u2019<\/span><\/h2>\n<p><span style=\"font-weight: 400;\"><img loading=\"lazy\" decoding=\"async\" class=\"alignright size-medium wp-image-12002\" src=\"https:\/\/www.spinalcure.org.au\/wp-content\/uploads\/2022\/04\/Mend-the-gap-image-300x170.jpg\" alt=\"Scientist looks through petrie dish\" width=\"300\" height=\"170\" srcset=\"https:\/\/www.spinalcure.org.au\/wp-content\/uploads\/2022\/04\/Mend-the-gap-image-300x170.jpg 300w, https:\/\/www.spinalcure.org.au\/wp-content\/uploads\/2022\/04\/Mend-the-gap-image-1024x579.jpg 1024w, https:\/\/www.spinalcure.org.au\/wp-content\/uploads\/2022\/04\/Mend-the-gap-image-768x434.jpg 768w, https:\/\/www.spinalcure.org.au\/wp-content\/uploads\/2022\/04\/Mend-the-gap-image.jpg 1362w\" sizes=\"(max-width: 300px) 100vw, 300px\" \/>One of the first areas of research the team is investigating involves using injectable gels into the spinal cord. These gels contain tiny magnetic rods that are controlled with magnets to provide a scaffold to direct the regrowth of neurons.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">When the spinal cord is damaged, small breaks in the cord stop impulses travelling from the brain to limbs. These gaps, <\/span><span style=\"font-weight: 400;\">typically a few centimetres wide<\/span><span style=\"font-weight: 400;\">, prevent people from making full recoveries after spinal cord injuries.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Mending these gaps has been one of the biggest challenges in spinal cord injury rehabilitation.\u00a0\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The new technique is minimally invasive using machine-vision-equipped surgical robots to inject the gel. The gel can also be shaped to match the type of lesion that someone has sustained making it more personalised to their injury. These techniques are still limited to animal studies but enormous progress has been made.\u00a0<\/span><\/p>\n<h2>Other areas being investigated<\/h2>\n<p><span style=\"font-weight: 400;\">Multiple types of therapy are likely to be used in spinal cord rehabilitation.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Mend The Gap are also looking at the potential of infusing drugs into the hydrogels to help with the healing process in the spinal cord. This could include drugs that help protect stem cells within the spinal cord.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Other possibilities include biomaterials that help with the breakdown of the scar that forms after a spinal cord injury. Internationally renowned researcher Professor Molly Schoichet who is a member of Mend The Gap has <\/span><a href=\"https:\/\/news.engineering.utoronto.ca\/re-engineered-enzyme-could-help-reverse-damage-from-spinal-cord-injury-and-stroke\/\"><span style=\"font-weight: 400;\">recently redesigned such an enzyme<\/span><\/a><span style=\"font-weight: 400;\"> that removes scar tissue to be more efficient and last longer within the spinal cord.\u00a0<\/span><\/p>\n<h2>Acceleration of research to benefit all<\/h2>\n<p><span style=\"font-weight: 400;\">It\u2019s important to note that human trials are a long way off for these biomaterials and injectable gels.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The team will be looking at many potential treatment options and research questions.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">However, this is an exciting time for the world of spinal cord injury research, and the collaboration is an important aspect in pushing forward research progress. The team will undoubtedly accelerate the research and push it in the right direction.\u00a0<\/span><\/p>\n<blockquote><p><span style=\"font-weight: 400;\">We aim to bring any promising discoveries to Australia to help benefit all Australians living with spinal cord injuries.\u00a0<\/span><\/p>\n<p>Find out <a href=\"https:\/\/www.spinalcure.org.au\/research\/our-research-funding\/\">more about our research<\/a>.<\/p><\/blockquote>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"<div class=\"entry-summary\">\n<div class=\"entry-summary\">\nA new international team of 32 scientists has joined forces to identify areas of promising research in spinal cord injuries. Their first project aims to mend the tiny gaps that form after a traumatic injury, writes Tom Elphick, SpinalCure Community&hellip;\n<\/div>\n<div class=\"link-more\"><a href=\"https:\/\/www.spinalcure.org.au\/research\/new-panel-of-experts-aims-to-mend-the-gap-in-spinal-cord-injuries\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &ldquo;New panel of experts aims to \u2018mend the gap\u2019 in spinal cord injuries&rdquo;<\/span>&hellip;<\/a><\/div>\n<\/div>\n<div class=\"link-more\"><a href=\"https:\/\/www.spinalcure.org.au\/research\/new-panel-of-experts-aims-to-mend-the-gap-in-spinal-cord-injuries\/\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &ldquo;New panel of experts aims to \u2018mend the gap\u2019 in spinal cord injuries&rdquo;<\/span>&hellip;<\/a><\/div>\n","protected":false},"author":1,"featured_media":12002,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[22,26],"tags":[36,65,79,43,61,78,84,33],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.6 - 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