New developments in soft neural interfaces are enabling the delivery of electrical and chemical stimulation to the spinal cord. The stimulations restored locomotion in animal models of paralysis. The soft interfaces can be placed either below or above the dura mater in the spinal cord. The subdural location combines many advantages, including increased selectivity of electrical stimulation, lower stimulation thresholds and targeted chemical stimulation through drug delivery. This technique is important as it reduces power consumption and risks of long-term damage to the tissue.
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