Introduction

Schwann cell clinical trial approved for chronic spinal cord injury

Schwann cell clinical trial approved for chronic spinal cord injury

The Miami Project to Cure Paralysis has received the green light from the U.S. FDA to proceed with a Phase I clinical trial to evaluate the safety of autologous human Schwann cell transplantation for chronic spinal cord injuries.

The team is already conducting a similar trial subacute SCI. The new trial will be conducted in parallel and focus on individuals that are at least 1 year post-injury. Each participant’s own Schwann cells will be obtained from their sural nerve – found in the lower leg – and cultured to generate sufficient numbers. The cell therapy will be combined with an intense exercise and rehabilitation intervention to maximize outcome.

Read more…