Introduction

Induced pluripotent stem cell-derived neural cells survive and mature in the nonhuman primate brain

Induced pluripotent stem cell-derived neural cells survive and mature in the nonhuman primate brain

Researchers at the University of Wisconsin have taken fibroblasts from the brains of rhesus monkeys with Parkinsons, then reprogrammed these into induced pluripotent stem cells. These were then encouraged to grow into neural progenitors before being transplanted back into the monkeys’ brains.

The cells survived for up to 6 months and differentiated into neurons, astrocytes, and myelinating oligodendrocytes. An encouraging result for personalised CNS therapies.

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